Nisus Software, Inc. produces Nisus Email, a simple but full-featured email client whose claim to fame is its ability to allow you to compose messages in your favorite text editor or word processing program.
Please note that, while the software remains available, it hasn't been updated in quite some time.
Currently, no user reviews have been submitted. Send me yours!
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Also, if you have an older Mac, be sure to check out the "Classic" applications page for more options.
Finally, take a look at ALEMIA if you think you know that name of an application, but aren't quite sure.
Graham Orndorff has written a superb collection of articles on setting up email servers and secure email clients on Mac OS X.
Adam Engst has put together a comprehensive overview of email attachment formats that is invaluable for anyone who wants or needs to understand the complexities behind them.
These are applications that are newer and of potential interest, but which I haven't yet selected for permanent inclusion. Have a look, and let me know if you think they deserve to be part of the permanent collection!